Harlan Laboratories has a broad background and expertise in performing analyses in support of mammalian and ecotoxicology studies on industrial chemicals, agrochemicals, biocides and pharmaceutical products.
With modern, purpose-built facilities, the Harlan Laboratories analytical team has extensive experience in performing chemical analyses of difficult substances with challenging physico-chemical properties. Our laboratories are equipped with state-of-the-art instrumentation and offer a comprehensive array of analytical techniques such as:
MaXis TOF-MS, HPLC-MS/MS, ICP-MS, HPLC, IC, GPC GC, GC-MS, UV/Vis, FT-IR, AAS.
Analytical testing conducted within Harlan Laboratories includes, but is not limited to:
- Analysis of dose formulations and tissues for mammalian studies
- Test item characterization and analysis of air chambers for inhalation studies
- Analysis of dose solutions, aqueous, soil, sediment and tissue samples for ecotoxicology studies
- Analytical method development and validation in study-specific matrices
- Specific analyte determinations in various matrices
- Purity and impurity determinations on products and formulations (REACH, 5-batch)
- Spectra and structural elucidation studies (e.g., unknown impurities in 5-batch studies)
- Isolation and certification of unknown impurities
- Residue analysis of environmental samples
- Overall and specific migration studies
Our analytical laboratories are very familiar with many sample extraction techniques such as:
- Liquid/liquid extraction
- Solid Phase Extraction (SPE)
- Twister and Solid Phase Micro Extraction (SPME)
- Accelerated Solvent Extraction (ASE)
Harlan's analytical facilities operate to GLP requirements, but can conduct studies without GLP compliance. We are able to operate in a principal investigator role for multi-site studies, if required.
In addition, our staff is able to provide advice and recommendations on study design, particularly for bespoke analytical studies.