Overview
Harlan Laboratories can currently perform polyclonal antibody
production and custom polyclonal production in a variety of
different species including: mouse, rat, guinea pig, rabbit, sheep,
goat, pig, camalid, bovine, dog, primate, chicken and birds. If you
require production in any animals not listed, pleased contact us.
The use of chickens to produce polyclonal antibodies has increased
in popularity as there are many advantages over traditional
antibodies from mammals.
- Chickens produce large amounts of antibody (IgY) in their
eggs.
- Chickens can be used to produce antibodies against highly
conserved mammalian antigens which do not elicit a response in
mammals.
- The IgY produced does not bind to the mammalian Fc receptor;
which means very low background signals.
- Chicken antibodies do not react with Rheumatoid Factors in
mammalian serum which can cause false positives when analyzing
auto-immune disease serum.
- IgY does not activate the mammalian complement pathway.
As with all our other polyclonals, Specific Pathogen Free (SPF)
chickens are used to ensure production of high quality antibodies
without interference or cross-reactivity due to the presence of
antibodies to common poultry pathogens.
For providing the optimal service and communication in providing
you a high quality end product and to fulfill legal requirements,
we ask you to fill out some information sheets, which include:
Contact us at antibodies@harlan.com for
polyclonal antibody production and custom polyclonal production
pricing and additional information.