We can help you in adding a test compound or ingredient to a
diet. This is often a convenient approach to dosing research
animals. We refer to these compounds as "Customer Supplied
Ingredients" or "Customer Reserves", and they can be added to most
diets. The investigator supplies these compounds to us. Please contact us for
further information.
Click here for Customer Supplied Ingredient Submission
Form.
When adding a compound to a diet, there are some important
considerations:
Safety
We require a Material Safety Data Sheet (MSDS) or
other relevant safety and usage information. We have an obligation
to maintain a safe work environment. This typically applies to
drugs, experimental compounds and chemicals. Food products
generally will not require safety information, although information
about nutrient content, reason for use, etc. is helpful in the
design of diets.
Stability (water,
heat)
Water is added as a pelleting aid. Pellets are formed under
pressure but no external heat is applied. Sometimes the drying
process can be modified if heat stability is questioned. It is your
responsibility to determine the suitability of the compound for
inclusion into a pelleted diet.
Stability (irradiation)
If you require irradiation, we can customize most diets to
be suitable for this sterilization process. Once your diet has been
produced, we can send it for irradiation. The dose ranges from
20-50 kGy. Diets that are to be irradiated require an additional 2
weeks for shipment (4 weeks total). For diets that are to be
irradiated, vacuum packaging may also be beneficial. Both
irradiation and vacuum packaging MUST be requested when ordering.
It is your responsibility to determine the suitability of the
compound for irradiation.
Inclusion Rate
Please let us know, on a g/kg diet or percentage basis, how much of
the compound you want in the diet. If you have in mind a dose based
on animal body weight, we can help convert that to g/kg diet.
Quantity of Compound to
Send
Please send extra compound (approximately enough for one more kg
than you have ordered) so that we can yield the desired amount of
diet. If you do not send enough compound, we will use the entire
amount and make as much diet as possible, unless special
arrangements can be made.
Inventory of the
Compound
If you plan to use the compound more than once &
stability with storage is not an issue, we will maintain an
inventory for you and store it appropriately, per your
instructions. Otherwise, we will return any remaining compound with
your shipment. We will not be responsible for disposing of the
compound.
For general information, please contact us at tekladinfo@harlan.com.
For technical questions, please contact us at askanutritionist@harlan.com.