Athymic Nude Rats

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The Athymic nude mutant rat was derived from animals obtained from the Rowett Research Institute, Aberdeen, Scotland.

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Athymic Nude Rats - US
Health Monitoring Reports
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AthymicNude_MutantRat

Characteristics

  • Coat: Hooded (pigmented)
  • The rnu allele on chromosome 10 is an autosomal recessive mutation associated with hairlessness and thymic aplasia
  • The thymus-dependent lymph node areas are depleted of lymphocytes (T-cells)
  • Phenotypically hairless (sparse hair growth possible)
  • Rudimentary thymic tissue
  • Increased Natural Killer (NK) cell population
  • Foxn1rnu/Foxn1+ heterozygotes do not show partial expression of rnu phenotype

Research Use

  • Oncology
  • Immunology
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