C57BL/6 Inbred Mice

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Strains

Originated in 1974, from the Jackson Laboratory, Bar Harbor, Maine, to the Laboratory Animal Centre,Carshalton UK; to OLAC (now Harlan Laboratories) in 1983.

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C57BL/6 (JOlaHsd) Inbred Mice - Euro

Additional Available Data

  • Hematology
  • Clinical chemistry
Health Monitoring Reports
Location Report
Barrier 700 West Download PDF
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C57BL_6_InbredMice

Characteristics

  • Coat: Black
  • Litter average: U.S.: 6.0 EU: 6.5
  • Haplotype: H-2b
  • Most widely-used inbred strain
  • Low tumor incidence
  • High preference for alcohol
  • Microphthalmia
  • Incidence of hydrocephalous
  • The C57BL/6JRccHsd subline does not carry the Nnt (nicotinamide nucleotice transhydrogenase) gene deletion
  • The C57BL/6JOlaHsd subline carries a deletion at the alpha synuclien locus

Research Use

  • Background for induced and genetically-modified models
  • Diet-induced obesity
  • Toxicology
  • Aging
  • Cardiovascular
  • Superovulation
  • Behavior and learning disabilities
  • Immunology
  • Drug addiction
  • Alcoholism
  • General studies
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