NMRI Nude Mice

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NMRI-nu_-ISO-42+34_2010

Additional Available Data

Health Monitoring Reports
Location Report
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NMRINude_MutantMice

Characteristics

  • Coat: Albino
  • Litter Average: 7
  • The nu allele on chromosome 11 is an autosomal recessive mutation
  • Dysfunctional rudimentary thymus
  • Phenotypically hairless (sparse, intermittent hair growth possible)
  • T-cell deficient
  • B-cells function normal
  • No generation of cytotoxic effector cells
  • No graft versus host response
  • Foxn1nu/Foxn1+ heterogygotes do not show partial expression of the nu phenotype

Research Use

  • Oncology
  • Transplantation
  • Tumor cell growth
  • Immunology
  • Autoimmune disease
  • Antibody production
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