NOD Inbred Mice

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Strain

This strain is cryopreserved.

Please contact us at technicalservices@harlan.com for assistance with revitalization and contract breeding.

Characteristics

  • Coat: Albino
  • Approximately 80% of females and 20% of males develop insulin-dependent diabetes mellitus (IDDM) by thirty weeks of age
  • Spontaneously develop autoimmune diabetes
  • Higher locomotor activity in open-field than C57BL/6 mice
  • Have unique MHC class II haplotype
  • Low susceptibility to Mycobacterium leprae

Research Use

  • Diabetes
  • Autoimmunity
  • Hyperglycemia
  • Glucosuria
  • Insulitis
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