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View more mutant mice

Country of Origin(Select One)

The NOD.SCID mutant mouse was received by National Cancer Institute, Frederick, Maryland, in 2004. Harlan acquired from National Cancer Institute in 2006.

DownloadGrowth Curve
NOD.SCID Mutant Mice - US

Additional Available Data

Health Monitoring Reports
Location Report
Indianapolis, IN - 265I Download PDF
Livermore, CA - 237I Download PDF
Livermore, CA - 239 Download PDF
Madison, WI - 203I Download PDF
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  • Coat: Albino
  • Autosomal recessive, single nucleotide polymorphism with Prkdc gene on chromosome 16
  • Severe combined immunodeficiency affecting T- and B-lymphocyte development
  • Natural Killer (NK) cell, macrophage and granulocyte numbers and function are reduced
  • As SCID mice age, a variable percentage become "leaky" from spontaneous development of functional T- and B-lymphocytes
  • Highly susceptible to opportunistic viral and bacterial infection
  • Development of autoimmune diabetes does not occur due to severe combined immunodeficiency
  • Spontaneous thymic lymphomas

Research Use

  • Oncology
  • Transplantation
  • Tumor cell growth
  • Immunology
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