SAM (Senescence Accelerated Mice) Inbred Mice
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This strain is under consideration for maintenance and cryopreserved repository.
SAM models were developed from AKR/J by Kyoto University. Five litters with severe senescense were selected to further propogate and examine these characteristics. Litters that showed normal aging were selected as a senescence-resistant series (R-series). The genetic background of the SAM mice bacame suspect after the pathological findings were different from the AKR/J mouse. Each SAM model is genetically different. Each SAM colony was acquired by Harlan by Takeda Chemical Ltd. in 2002.
| Health Monitoring Reports |
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| Blackthorn - G Block |
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Order code: 953
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Research Use
- Accelerated senescence studies
- Geriatric pathogenesis
- Senile amyloidosis (apolipoprotein A-II)
- Hearing impairment
- Emotional disorders
- General purpose model
- Aging process
- Age-dependent disorders
- Senile osteoporosis
- Hyperinflation of the lungs
- Deficits in learning and memory
- Brain atrophy
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