SCID Mice

View more mutant mice

Strains

Produced in

Harlan acquired the SCID from the Fox Chase Cancer Center, Philadelphia, Pennsylvania, in 1991.

Health Monitoring Reports
Location Report
Blackthorn - Isolator 162 Download PDF
Blackthorn - Isolator 167 Download PDF
Pricing

Pricing unavailable.

Order code: 881 Initiate your order via our online form

Characteristics

  • Coat: Albino or Agouti
  • Autosomal-recessive, single-nucleotide polymorphism within Prkdc gene on chromosome 16
  • Severe combined immunodeficiencyaffecting T- and B-cell development
  • Natural Killer (NK) cell, macrophage, and granulocyte cell numbers and function are normal
  • As SCID mice age, a variable percentage become “leaky” from the spontaneous development of functional T and B lymphocytes
  • Highly susceptible to opportunistic viral and bacterial infection

Research Use

  • Oncology
  • Transplantation
  • Tumor cell growth
  • Immunology
Find similar models cancel

Related Downloads & Links

Diets Information

To contact a specialist, select your region