| Frequently Asked Questions |
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| What surgical services does Harlan Laboratories currently offer? |
| Harlan currently offers vascular and non-vascular cannulations in rats, soft tissue procedures in rats and mice, and implantation of various devices in rats and mice. Harlan commonly develops procedures specific to client requests. Please contact Technical Services for a rodent surgical service that is currently unlisted. |
| What catheter material does Harlan Laboratories utilize? |
| Our standard catheter material is polyurethane. However, other catheter materials such as polyethelene, silicone or Culex catheters are available upon request. |
| What is Harlan Laboratories' standard exteriorization? |
| Harlan's standard exteriorization is a subcutaneous pouch with a fixed exteriorization. At the exteriorization point, located between the scapula on the dorsal surface of the rat, all catheters are 3.5 french and can be accessed with a 22 or 23 gauge blunt tip needle. Modifications to the subcutaneous pouch such as rat jackets, harnesses, injection ports, and vascular access ports are also available upon request. |
| What is Harlan Laboratories' standard locking solution? |
| Harlan's standard locking solution is heparinized glycerol (500 IU/mL). Mixing instructions for this solution are listed in the table above. Additional locking solutions are available upon request, such as heparinized dextrose, heparinized saline and tauroldine citrate. |
| Where are Harlan Laboratories' surgical facilities located? |
| Harlan currently operates three barrier dedicated surgical units. These facilities are located in Indianapolis, IN, Livermore, CA and Dublin, VA. Surgically modified immunodeficient rodent models are available from Madison, WI and Somerville, NJ. |
| What anesthetics are used by Harlan Laboratories? |
| Harlan's standard anesthetic protocol utilizes an intraperitoneal injection of a ketamine/xylazine cocktail. Inhalant isolflurane is also utilized. There is no additional charge for either type of anesthetic. |
| Does Harlan Laboratories provide analgesics to surgically modified animals? |
| Yes, animals undergoing major survival surgery routinely receive post-operative analgesia to further ensure their humane and ethical care. Harlan's standard analagesic is ketoprofen, a non-steroidal anti-inflammatory (NSAID), administered via subcutaneous injection. Alternative analgesics may be used based upon Client project requirements. Please specify this special request at the time of ordering. |
| How soon will I receive my surgically modified animals, after placing my order? |
| Typically, orders for surgically modified animals require 1-2 week's notice. Harlan will process your order as soon as possible. Standing orders are encouraged. Requests for special materials or procedures may require addtional time, prior to being able to complete your order. |
| What is the rounded tip catheter? |
| The rounded tip catheter offers reduced maintenance requirements, with a recomended flushing interval of 5-7 days and long-term patency benefits. This catheter is Harlan's standard for the jugular vein, femoral vein, portal vein, carotid artery and femoral artery . |
| I am receiving dual cannulated rats. How will I determine the difference between the two catheters? |
| Each catheter is identified with a silk screened silicone sleeve. The silicone sleeve indicates which type of catheter is inserted. This sleeve should remain on the catheter. However, the sleeve can be removed by lubricating the area and sliding the sleeve off the tip of the catheter. |
| Who should I contact for further information? |
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Please contact Technical Services, for additional information.
Phone: (800) 473-6423
Email: SurgicalServices@harlan.com
Your sales representative or customer services representative are also available for further information regarding Harlan Laboratories' surgical services.
Customer Service: (800) 793-7287
Email: askharlan@harlan.com
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