B10.D2-H-2^d/n Congenic Mice

Nomenclature: B10.D2-H-2^d/nOlaHsd

B10 Congenic Mice Origin

• This B10 congenic mouse was developed by George D. Snell, the Jackson Laboratory, Bar Harbor, to GD Searle, High Wycombe. From GD Searle to OLAC (now Harlan Laboratories) in 1978.
• The inbred partner is C57BL/10Sn and the donor strain is DBA/2

B10 Congenic Mice Characteristics

• Coat: Black
• Haplotype: H-2^d
• Mean survival 122 ± 4.0 weeks

B10 Congenic Mice Research Use

• Low antibody affinity and small quantity of antibody produced in B10.D2/n
• High immune response to ferritin in C57BL/10 and congenic lines B10.M, B10.D2, B10.BR and B10.A
• This congenic line is highly susceptible to infection by Salmonella typhimurium strain C5.

Harlan Laboratories' Production 

• We maintain on Teklad Global Diet 2018S within maximum security production facilities.