BALB/c Congenic Mice

C.C3H-H-2k

 

Nomenclature: C.C3H-H-2k/OlaHsd

This strain is cryopreserved.  Please contact us at Harlancommunications@harlan.com or call Technical Service for assistance with revitalization and contract breeding of this model.

Information and Research Data
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C.C3H-H-2k Data Sheet

BALB/c Congenic Mice Origin

  • The C.C3H-H-2k/OlaHsd congenic line is developed by Dr. Frank Lilly, Department of Genetics, Albert Einstein College of Medicine, New York. From Stanford University, California, to Clinical Research Centre, Harrow. From Clinical Research Centre to OLAC (now Harlan Laboratories) in 1977.

BALB/c Congenic Mice Characteristics

  • Coat: Albino
  • Haplotype:  H-2k
  • The inbred partner is BALB/cJ and the donor strain is C3H, resulting in the differential locus H-2k 
  • Following administration of murine cytomegalovirus, BALB/c, BALB.B, and BALB.K mice develop persistent myocarditis regardless of age at infection, and age-related cardiopathy is frequent and severe in infected and uninfected mice
  • Resistant to infection with Onchocerca lienalis
  • Early development of lymphocytic choriomeningitis, compared to C3H/HeJ and CBA/H

BALB/c Congenic Mice Research Use

  •  Immunology

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