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Research Models and Services
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Facility management
Maximum barrier design and construction.
Strictly controlled barrier access.
Personnel are required to shower prior to barrier entry.
Protective clothing, including gloves, hair cap, and mouth mask, is worn in all SPF units.
HEPA-filtered 99.9% fresh air supply. Positive pressure relative to outside is maintained in all areas.
All diet, bedding, and other supplies are autoclaved, irradiated, or otherwise decontaminated prior to barrier entry.
Emergency generator to safeguard integrity of barrier.
Acidified/chlorinated and filtered (0.2 micron) automatic drinking water.
Environmental controls that meet or exceed applicable standards and regulations.
Light cycle: 12 hours light – 12 hours dark.
Heating and ventilation systems are capable of supplying 15 air changes per hour.
Colony management
Unrelated breeders carefully selected to maintain colony heterogeneity and productivity.
Production in trios (two males with one female) with postpartum mating.
Births are recorded daily; weaning at 3 weeks.
Rigorous sanitation to safeguard animal health and to minimize research variables.
Use of standardized Teklad diets (ad libitum) to optimize nutrition.
Comprehensive health monitoring program, meeting and exceeding FELASA recommendations.
Daily colony observation by trained animal care technicians.
Animals are bred and maintained in polypropylene cages, meeting EU Guidelines.
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