Lewis Inbred Rat

Nomenclature:

US Strain: LEW/SsNHsd
EU Strain:: LEW/Han^™Hsd  

Lewis Rat Origin

• LEW/SsNHsd:  This Lewis inbred rat was derived from a nucleus colony obtained from the National Institutes of Health, Bethesda, Maryland.
• LEW/Han^™Hsd: This version of the Lewis inbred rat line came to Central Institute for Laboratory Animal Breeding, Hannover, in 1973 at F58. To Harlan Nederland in 1994 through acquisition of Central Institute for Laboratory Animal Breeding.

Lewis Rat Characteristics

• Coat: Albino
• Litter average: 7.5
• Haplotype: RT1^l
• Docile disposition
• Susceptible to induction of autoimmune disease
• Inbred recipient for several congenic strains
• Increased levels of serum thyroxine, insulin, and growth hormone

Lewis Rat Research Use

• Experimental allergic encephalomyelitis
• Adjuvant-induced arthritis
• Transplantation

Harlan Laboratories' Production

• We maintain on  Teklad Global Diet 2018S within maximum security production barrier facilities.