Albino C57BL/6 Mice

Nomenclature: C57BL/6-Tyr^c/BrdCrHsd

 Albino C57BL/6 Mice Origin

• From Allan Bradley at Baylor College of Medicine to National Cancer Institute (NCI) in 2000; to Harlan in 2008.
   

Albino C57BL/6 Mice Characteristics

• Coat: Albino
• Contains a mutation in the c (tyrosinase) gene
• Litter Average: 6.5
• Haplotype: H-2^b

Albino C57BL/6 Mice Research Use

• Source of albino C57BL/6 embryos for chimera generation
• Ovarian transfer

Harlan Laboratories' Production

• We maintain on Teklad Global Diet 2018S within a maximum security production facililty

References:

1.  Klysik, J., Dinh, C., and Bradley, A.  (2004) Two new mouse chromosome 11 balancers.  Genomics, 83 (2).  303-310. 

2.  Kopp, C., et al. (2002). Homeostatic sleep regulation is preserved in mPer1 and mPer2 mutant mice.  European Journal of Neuroscience, 16 (1). 1099-1106.

3.  Lui P., et al. (1998).  Embryonic lethality and tumorigensis caused by segmental aneuploidy of mouse chromosome 11.  Genetics, 150 (1).  1155-1168.

4.  Prosser, H.M., et al. (2007).  Prokinectin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei. Proceedings of the National Academy of Sciences, 104 (2). 648-653.